Endocrine Abstracts

Introduction: Hypothyroidism in pregnancy may be associated with neurodevelopmental delay of the unborn baby. Timely management of abnormal thyroid function tests (TFTs) in pregnancy is important. In our centre, some patients attend an Endocrinology-led dedicated antenatal thyroid clinic, whilst others attend an Obstetrician-led general antenatal clinic.Objectives: The management of hypothyroid pregnant patients attending our centre was audited against T...

Background: Maternal obesity during pregnancy is associated with adverse effects on fetal growth and development. As the placenta is a key organ regulating fetal growth, we hypothesized that maternal obesity is associated with altered placental expression and DNA methylation of genes regulating fetal growth and glucocorticoid metabolism and aimed to investigate this in first trimester (F; <12 weeks gestation) and term (T;>37 weeks gestation) placental tissues.<p cl...